Sunday, November 3, 2024
Home Health News Researchers reveal systemic health impact of microplastic exposure using fruit fly model

Researchers reveal systemic health impact of microplastic exposure using fruit fly model

by Medical Xpress
0 comment


Credit: Unsplash/CC0 Public Domain

A research team led by Prof. Li Lei and Prof. Liu Chang from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) has revealed the significant systemic health impact of microplastic (MP) exposure, using the terrestrial model organism Drosophila melanogaster (fruit fly). The study was published in Zoological Research.

Plastics, including microplastics, have become pervasive in our environment. According to the United Nations, more than 400 million tons of plastic are produced globally each year, with tens of millions of tons of plastic waste polluting oceans worldwide. Addressing plastic pollution has become a critical global imperative.

In this study, the researchers assessed the systemic toxicity of MPs in by concentrating on key aspects of general , including sleep patterns, lifespan, and fecundity. The fruit flies were fed diets spiked with two distinct concentrations of MPs: 1×MPs at 0.02 mg/mL and 10×MPs at 0.2 mg/mL. The exposure periods encompassed various developmental stages, spanning from 2 days to 10 weeks.

Experimental results showed that MP exposure led to intestinal damage, disrupted sleep patterns, reduced ovary size, shortened lifespan, and genotoxic effects revealed by RNA-seq analysis.

Moreover, while microplastics did not penetrate the brain or ovaries, transcriptome analysis showed genotoxic effects impacting inflammation, circadian regulation, and in the ovary, proteolysis, and carbohydrate metabolism processes in the brain.

“Our research indicates that microplastics pose a comprehensive threat to the health and longevity of organisms, extending far beyond the previously understood organ-specific effects,” said Prof. Li and Prof. Liu.

This underscores the urgency of addressing environmental pollution, given its widespread detrimental impacts on health and , Li added.

More information:
Wei Yan et al, Microplastic exposure disturbs sleep structure, reduces lifespan, and decreases ovary size in Drosophila melanogaster, Zoological Research (2024). DOI: 10.24272/j.issn.2095-8137.2024.038

Provided by
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences

Citation:
Researchers reveal systemic health impact of microplastic exposure using fruit fly model (2024, August 13)
retrieved 13 August 2024
from https://medicalxpress.com/news/2024-08-reveal-health-impact-microplastic-exposure.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.





Source link

You may also like

Leave a Comment

Edtior's Picks

Latest Articles

All Rights reserved, site designed by Yellohost.co.za